What is Phosphatidylserine (PS)
It includes amino and fatty acids such as docosahexaenoic acid (DHA).
It is a phospholipid that is vital to your brain cells. Phospholipids are molecules containing both amino and fatty acids found in every cell membrane within our bodies. The fatty acids include omega-3 and omega-6 fatty acid molecules—essential for life.
It has many known functions throughout all of our tissues and organs, but is most important as the key building block for the billions of cells that make up our brain.
First isolated in 1942, it is now available as a dietary supplement derived from soy lecithin.
Possible Health benefits
PS increases metabolism throughout your entire brain.
(Left:) PET imaging of the brain of a 59-year-old woman. The color scale indicates regional glucose metabolism at three brain levels, red is most intense and blue is least. UPPER: before PS; LOWER: after taking 500 MG PS daily for three weeks. Metabolism is increased in almost all brain regions. Over 3,000 published research papers and more than 60 clinical trials have established that it can rejuvenate your brain cell membranes and thereby:
1.Memory and cognition
Early studies of it distilled the chemical from bovine brain. Because of concerns about Bovine Spongiform Encephalopathy, however, modern studies and commercially available products are made from soybeans. The fatty acids attached to the serine in the soy product are not identical to those in the bovine product, which is also impure. Preliminary studies in rats indicate that the soy product is at least as effective as that of bovine origin. However, later clinical trials in humans found that "a daily supplement of S-PS (soybean derived PS) does not affect memory or other cognitive functions in older individuals with memory complaints."
On May 13, 2003, the U.S. Food and Drug Administration stated "based on its evaluation of the totality of the publicly available scientific evidence, the agency concludes that there is not significant scientific agreement among qualified experts that a relationship exists between it and reduced risk of dementia or cognitive dysfunction." FDA also stated "of the 10 intervention studies that formed the basis of FDA's evaluation, all were seriously flawed or limited in their reliability in one or more ways." It concludes that "most of the evidence does not support a relationship between it and reduced risk of dementia or cognitive dysfunction, and that the evidence that does support such a relationship is very limited and preliminary." FDA did, however give "qualified health claim" status to it, stating that "Consumption of it may reduce the risk of dementia in the elderly" and "Consumption of it may reduce the risk of cognitive dysfunction in the elderly".
It has been demonstrated to speed up recovery, prevent muscle soreness, improve well-being, and might possess ergogenic properties in athletes involved in cycling, weight training and endurance running. Soy-PS, in a dose dependent manner (400 mg), has been reported to be an effective supplement for combating exercise-induced stress by blunting the exercise-induced increase in cortisol levels. PS supplementation promotes a desirable hormonal balance for athletes and might attenuate the physiological deterioration that accompanies overtraining and/or overstretching. In recent studies, PS has been shown to enhance mood in a cohort of young people during mental stress and to improve accuracy during tee-off by increasing the stress resistance of golfers.
3.Attention-deficit hyperactivity disorder
First pilot studies indicate that PS supplementation might be beneficial for children with attention-deficit hyperactivity disorder.
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